Personalized Behavioral Nutrition Among Older Asian Americans: Study Protocol.
Personalized Behavioral Nutrition Among Older Asian Americans: Study Protocol.
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DOI：
10.1097/nnr.0000000000000514
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发表时间：
2021-07-01
期刊：
影响因子：
2.5
通讯作者：
Li C
中科院分区：
文献类型：
--
作者：
Ko J;Wang J;Du Y;Jiwani R;Li C
代谢组学分析是对复杂饮食模式的代谢反应的客观评估。然而，很少有研究调查与个性化行为营养（PBN）干预相关的潜在益处，这些干预措施结合了代谢组学方法，可改善老年亚裔美国人（AAs）2型糖尿病（T2D）的糖尿病结局。本文描述了一项试验性研究的方案，该研究测试了营养干预的自我管理，提供了个性化的饮食建议，包括代谢物表型反馈和饮食和血糖的数字自我监测。共60名老年AA将随机分为两组：PBN组和对照组。PBN组的参与者将根据饮食和表型反馈使用的代谢概况获得个性化的饮食建议。本研究旨在探讨PBN对糖尿病结局的可行性和初步效果。该研究于2020年9月开始，预计到2021年底完成数据收集。这项试点研究的结果将为未来的研究提供信息，为T2D患者制定个性化的营养干预措施。
Metabolomics profiling is an objective assessment of metabolic responses to intricate dietary patterns. However, few studies have investigated the potential benefits associated with personalized behavioral nutrition (PBN) interventions incorporating the metabolomics approach for improving diabetes outcomes for older Asian Americans (AAs) with type 2 diabetes (T2D). This article describes the protocol for a pilot study testing self-management of a nutrition-intervention-provided personalized dietary advice incorporating metabolites phenotypic feedback and digital self-monitoring of diet and blood glucose. A total of 60 older AAs will be randomized into two groups: a PBN group and a control group. Participants in the PBN group will receive personalized dietary advice based on dietary and phenotypic feedback-used metabolic profiles. This study aims to examine the feasibility and preliminary effects of the PBN on diabetes outcomes. The study began in September 2020, with estimated complete data collection by late 2021. Findings from this pilot study will inform future research for developing personalized nutrition interventions for people with T2D.