Female lordosis pattern in the male rat induced by estrogen and progesterone: effect of interruption of the dorsal inputs to the preoptic area and hypothalamus.
Female lordosis pattern in the male rat induced by estrogen and progesterone: effect of interruption of the dorsal inputs to the preoptic area and hypothalamus.
复制标题
雌激素和孕激素诱导的雄性大鼠的雌性脊柱前凸模式：视前区和下丘脑背侧输入中断的影响。
DOI：
10.1507/endocrj1954.22.243
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发表时间：
1975
期刊：
影响因子：
--
通讯作者：
Y. Arai
中科院分区：
文献类型：
--
作者：
K. Yamanouchi;Y. Arai
去势雄性大鼠在第三天测试前连续2天给予50马克苯甲酸雌二醇（EB）和1毫克孕酮(P) 6-8小时，前倾行为非常罕见。8只大鼠中只有1只对性成熟雄鼠的坐骑有前凸反应。然而，在手术切除视前区（POA）和下丘脑的背侧传入神经后，同样处理的去势雄鼠前凸行为的发生率明显增加。19只大鼠中有12只出现前凸反应。在接受假神经分离的大鼠中发病率较低。这些结果表明，背侧输入到POA和下丘脑可能对雄性大鼠的前凸调节系统产生强直性抑制作用。
Lordosis behavior was very rare in castrated male rats which had been pretreated with 50 mug estradiol benzoate (EB) for successive 2 days and 1 mg progesterone (P) 6-8 hr prior to testing on the third day. Only one out of 8 rats displayed lordosis in response to mounts by the sexually matured males. However, the occurrence of lordosis behavior was markedly increased in similarly treated castrated males in which the dorsal afferents to the preoptic area (POA) and hypothalamus were removed by the surgical cut. Twelve out of 19 rats of the group showed lordosis response. The incidence was less frequent in rats receiving sham deafferentation. These results suggest that the dorsal inputs to the POA and hypothalamus may exert a tonic inhibitory influence on the lordosis mediating system in the male rat.