Valves for autonomous capillary systems
Valves for autonomous capillary systems
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DOI：
10.1007/s10404-007-0256-2
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发表时间：
2008-09-01
影响因子：
2.8
通讯作者：
Delamarche, E.
中科院分区：
文献类型：
--
作者：
Zimmermann, M.;Hunziker, P.;Delamarche, E.
自主毛细管系统（CS）是液体由于毛细管力而在其中移动的微流体系统。CS原则上可以将基于微流体的分析设备的高性能带到近患者和环境测试应用中。在本文中，我们展示了如何将毛细管阀可以增强CSs与新的功能，如延迟和停止微通道中的液体。该阀采用流动路径的突然变化的几何形状来延迟在微通道中移动的液体填充前沿。我们展示了如何将联合收割机延迟阀与毛细管泵相结合，防止液体沿着微流体通道的拐角的捷径，停止液体填充微通道从几秒钟到超过30分钟，使用两个液体前沿合并触发阀，以及使用会聚到触发阀的平行微流体路径对液体进行计时。总之，这些概念应该为被动微流体系统增加功能，而不偏离其最初的使用简单性。
Autonomous capillary systems (CSs) are microfluidic systems inside which liquids move owing to capillary forces. CSs can in principle bring the high-performances of microfluidic-based analytical devices to near patient and environmental testing applications. In this paper, we show how wettable capillary valves can enhance CSs with novel functionalities, such as delaying and stopping liquids in microchannels. The valves employ an abruptly changing geometry of the flow path to delay a moving liquid filling front in a wettable microchannel. We show how to combine delay valves with capillary pumps, prevent shortcuts of liquid along the corners of microfluidic channels, stop liquids filling microchannels from a few seconds to over 30 min, trigger valves using two liquid fronts merging, and time a liquid using parallel microfluidic paths converging to a trigger valve. All together, these concepts should add functionality to passive microfluidic systems without departing from their initial simplicity of use.