Unlocking the development- and physiology-altering 'effector toolbox' of plant-parasitic nematodes.
Unlocking the development- and physiology-altering 'effector toolbox' of plant-parasitic nematodes.
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DOI：
10.1016/j.pt.2023.06.005
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发表时间：
2023-07
影响因子：
9.6
通讯作者：
Beth Molloy;T. Baum;Sebastian Eves-van den Akker
中科院分区：
文献类型：
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作者：
Beth Molloy;T. Baum;Sebastian Eves-van den Akker
植物寄生虫利用寄主的发育可塑性引起深刻的发育和生理变化。在植物寄生线虫(PPN)的情况下，这些变化可以导致新植物器官的发育。尽管这些寄生虫的发育和生理改变能力在病理学上很重要，但历史上的研究一直集中在它们抑制免疫的能力上。我们认为，考虑到喂养部位的建立所涉及的戏剧性变化，PPN的发育和生理改变能力实际上完全有可能主导效应器--突出了用于发育和生理改变的新型高通量筛选的必要性。发现线虫“工具箱”的这一部分可以使生物技术成为可能，加强作物保护，并揭示基本寄主生物学本身。
Plant parasites take advantage of host developmental plasticity to elicit profound developmental and physiological changes. In the case of plant-parasitic nematodes (PPNs), these changes can result in the development of new plant organs. Despite the importance of the development- and physiology-altering abilities of these parasites in pathology, research has historically focused on their abilities to suppress immunity. We argue that, given the dramatic changes involved in feeding site establishment, it is entirely possible that development- and physiology-altering abilities of PPNs may, in fact, dominate effector repertoires – highlighting the need for novel high-throughput screens for development- and physiology-altering ‘tools'. Uncovering this portion of the nematode ‘toolbox' can enable biotechnology, enhance crop protection, and shed light on fundamental host biology itself.