Evaluating the timing of differences in activity related to depression symptoms across adulthood in the United States.
Evaluating the timing of differences in activity related to depression symptoms across adulthood in the United States.
复制标题
DOI：
10.1016/j.jad.2021.01.069
复制
发表时间：
2021-04-01
影响因子：
6.6
通讯作者：
Krafty RT
中科院分区：
文献类型：
--
作者：
Smagula SF;Capps CS;Krafty RT
在有抑郁症状/障碍的人中发现的相对活动缺陷可能会在一天中均匀累积，或者可能倾向于在特定的时间表现出来。后者的证据表明，在某些时候，最需要行为方法来减少抑郁及其对健康的影响。我们对在2005-2006年国家健康和营养检查调查中提供有效加速度计数据的参与者进行了二次数据分析(n=4390)。参与者根据≥10的患者健康问卷-9标准分界点(即，有或没有临床显著抑郁症状的人)进行分类。在混合模型检验中，加速计测量的两小时垃圾桶中的平均活动水平是因变量，以检验抑郁状态和活动水平之间的关系是否因一天中的不同时间而不同；以及是否有任何此类关系因年龄组(18-29岁、30-44岁、45-59岁和60岁以上)而不同。在30岁以上的成年人中，有抑郁症状的人在一天中的活动水平通常较低，但这些影响在早上几个小时最明显。我们发现，在18-30岁的人群中，与普遍的抑郁症状相关的活动水平没有差异。产生这些不同活动模式并赋予它们对情绪的影响的抑郁症病理生理学的核心方面没有被测量。在30岁及以上的成年人中，改善与抑郁相关的相对活动缺陷的努力可能会受益于考虑到早晨不活动的明显作用。
Relative activity deficits found in people with (verses without) depression symptoms/disorders may accumulate uniformly throughout the day, or they may tend to be expressed at specific times. Evidence for the latter would suggest times when behavioral approaches are most needed to reduce depression and its health consequences. We performed a secondary-data analysis of participants who contributed valid accelerometer data at the 2005–2006 National Health and Nutrition Examination Survey (n=4390). Participants were categorized according to the Patient Health Questionnaire-9 standard cut-point of ≥10 (i.e., people with versus without clinically significant depression symptoms). Average levels of accelerometer-measured activity in two-hour bins were the dependent variable in mixed models testing if the relationship between depression status and activity level differed by time of day; and if any such relations varied by age group (18–29 years, 30–44 years, 45–59 years, and 60+ years). In adults over the age of 30, people with depression symptoms had generally lower levels of activity across the day, but these effects were most markedly pronounced in the morning hours. We found no differences in activity levels associated with prevalent depression symptoms among people 18–30 years of age. Core aspects of depression pathophysiology that produce these different activity patterns and confer their effects on mood were not measured. In adults 30 years and older, efforts to ameliorate relative activity deficits associated with depression may benefit from considering the apparently outsized role of inactivity that occurs in the morning.
登录
查看更多内容
DOI：
10.1073/pnas.1010180107
发表时间：
2010-11-09
影响因子：
11.1
作者：
Vandewalle, G.;Schwartz, S.;Maquet, P.
通讯作者：
Maquet, P.
影响因子：
5.1
作者：
Varma, Vijay R.;Dey, Debangan;Zipunnikov, Vadim
通讯作者：
Zipunnikov, Vadim
精神病医院出院后的短期自杀风险。
影响因子：
25.8
作者：
Olfson M;Wall M;Wang S;Crystal S;Liu SM;Gerhard T;Blanco C
通讯作者：
Blanco C
DOI：
10.1111/j.2517-6161.1995.tb02031.x
发表时间：
1995-01-01
影响因子：
5.8
作者：
BENJAMINI, Y;HOCHBERG, Y
通讯作者：
HOCHBERG, Y
影响因子：
25.8
作者：
Kaup, Allison R.;Byers, Amy L.;Falvey, Cherie;Simonsick, Eleanor M.;Satterfield, Suzanne;Ayonayon, Hilsa N.;Smagula, Stephen F.;Rubin, Susan M.;Yaffe, Kristine
通讯作者：
Yaffe, Kristine