Changes in Electrocortical Brain Activity during Exchange Transfusions in Newborn Infants
Changes in Electrocortical Brain Activity during Exchange Transfusions in Newborn Infants
复制标题
新生儿换血期间大脑皮层活动的变化
DOI：
10.1159/000014241
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发表时间：
2000
期刊：
影响因子：
2.5
通讯作者：
M. van de Bor
中科院分区：
文献类型：
--
作者：
M. Benders;Janneke H. Meinesz;F. van Bel;M. van de Bor
在13名婴儿（平均胎龄36.3 ± 1.9周，出生体重2，800 ± 635 g）的17次交换输血期间，用脑功能监测仪连续记录脑皮层电活动（ECBA）。在每个停药和输注期结束时测定ECBA信号的最小和最大振幅以及带宽。停药期间平均动脉血压（MABP）以及最小和最大振幅降低，输注期间升高。最小和最大振幅变化非常小（<基线的6%），似乎主要与MABP变化相关。我们的结论是，交换输血确实会引起ECBA的微小变化，这可能与临床无关。
Electrocortical brain activity (ECBA) was recorded continuously with a cerebral function monitor during 17 exchange transfusions in 13 infants (mean gestational age 36.3 ± 1.9 weeks, birth weight 2,800 ± 635 g). The minimum and maximum amplitudes, and bandwidth of the ECBA signal were determined at the end of each withdrawal and infusion period. Mean arterial blood pressure (MABP), and the minimum and maximum amplitudes decreased during the withdrawal period and increased during the infusion period. The minimum and maximum amplitude changes were very small (< 6% of baseline) and appeared to be primarily associated with MABP changes. We conclude that exchange transfusions do cause minor changes in ECBA, which are probably not clinically relevant.