Smart catheter flow sensor for continuous regional cerebral blood flow monitoring
Smart catheter flow sensor for continuous regional cerebral blood flow monitoring
复制标题
智能导管流量传感器，用于连续局部脑血流量监测
DOI：
10.1109/icsens.2011.6127287
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发表时间：
2011
期刊：
影响因子：
--
通讯作者：
R. Narayan
中科院分区：
文献类型：
--
作者：
Chunyan Li;Pei;Zhizhen Wu;C. Ahn;J. Hartings;R. Narayan
本工作报告的发展，一种新型的智能导管流量传感器（SCF）的连续监测区域脑血流（CBF）。SCF采用周期性加热技术，而不是连续加热，并每5秒校准一次。这种方法确保了长期连续监测的零漂移，并可以为基于MEMS的薄膜传感器提供可靠的数据。此外，采用四线结构消除引线效应，并采用比率法测量SCF的电阻。因此，与桥式热扩散流量传感器相比，它更精确。在0 ~ 100 ml/min范围内，灵敏度为2.47mV/ml/min，线性相关系数R2 = 0.9969。通过温度和介质导热系数的补偿，系统的分辨率达到0.5ml/min，精度优于满量程的3 ml/min。
This work reports on development of a novel smart catheter flow sensor (SCF) for continuous monitoring of regional cerebral blood flow (CBF). The SCF employs a periodic heating technique rather than continuous heating and calibrates itself every 5 seconds. This approach ensures zero drift for long-term continuous monitoring and can provide reliable data with MEMS-based thin film sensors. In addition, it uses a 4-wire configuration to eliminate lead wire effect and employs ratiometric measurement to deduce the resistance of SCF. Hence, it is more precise when compared to the bridge-type thermal diffusion flow sensor. The developed SCF has a sensitivity of 2.47mV/ml/min in the range from 0 to 100ml/min with a linear correlation coefficient of R2 = 0.9969. It achieves a resolution of 0.5ml/min and an accuracy better than 3ml/min of full scale with both temperature and medium thermal conductivity compensation.