The Role, Challenges, and Support of Pulse Net Laboratories in Detecting Foodborne Disease Outbreaks
The Role, Challenges, and Support of Pulse Net Laboratories in Detecting Foodborne Disease Outbreaks
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DOI：
10.1177/00333549101250s207
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发表时间：
2010-05-01
影响因子：
3.3
通讯作者：
Besser, John
中科院分区：
文献类型：
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作者：
Boxrud, David;Monson, Timothy;Besser, John
近年来，由于食品中的肠道微生物，全国范围内发生了几起备受瞩目的食源性疫情，包括花生制品中的鼠伤寒沙门氏菌，辣椒中的圣保罗沙门氏菌和菠菜中的大肠杆菌O157：H7。PulseNet是国家食源性疾病监测分子分型网络，在检测每一次疫情中发挥了关键作用。PulseNet实验室使用细菌分型方法快速检测食源性疾病集群，这通常是疫情发生的第一个迹象。通过产品召回、餐馆关闭和其他机制，快速检测疫情可减少持续传播。通过大大提高疫情检测的灵敏度，Pulse Net使我们能够识别和纠正食品生产和分销系统中的问题，这些问题原本不会引起我们的注意。每年，数百万例可能可预防的食源性疾病病例导致数十亿美元的生产力损失和医疗保健费用。我们描述了Pulse Net实验室在检测食源性疫情方面发挥的关键作用，并讨论了Pulse Net实验室目前面临的挑战和潜在的改进，以更快地识别未来的食源性疫情。
In recent years, there have been several high-profile nationwide foodborne outbreaks due to enteric organisms in food products, including Salmonella Typhimurium in peanut products, Salmonella Saintpaul in peppers, and Escherichia coli O157:H7 in spinach. Pulse Net, the national molecular subtyping network for foodborne disease surveillance, played a key role in detecting each of these outbreaks.PulseNet laboratories use bacterial subtyping methods to rapidly detect clusters of foodborne disease, which are often the first indication that an outbreak is occurring. Rapid outbreak detection reduces ongoing transmission through product recalls, restaurant closures, and other mechanisms. By greatly increasing the sensitivity of outbreak detection, Pulse Net allows us to identify and correct problems with our food production and distribution systems that would not otherwise have come to our attention. Annually, millions of potentially preventable cases of foodborne illness result in billions of dollars in lost productivity and health-care expenses. We describe the critical role Pulse Net laboratories play in the detection of foodborne outbreaks and discuss current challenges and potential improvements for Pulse Net laboratories to more rapidly identify future foodborne outbreaks.