Chapter 7. Magnetic Nanogel-enabled Image-guided Therapy
Chapter 7. Magnetic Nanogel-enabled Image-guided Therapy
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第 7 章磁性纳米凝胶图像引导治疗
DOI：
10.1039/9781788010481-00109
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发表时间：
2017
期刊：
影响因子：
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通讯作者：
Nair Madhavan
中科院分区：
文献类型：
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作者：
Tomitaka Asahi;Takemura Yasushi;Nair Madhavan
近年来，纳米医学受到了相当大的关注。随着纳米技术的出现，具有各种功能的纳米材料已被开发用于纳米医学应用。在这些纳米材料中，磁性纳米颗粒由于其独特的磁性在广泛的生物医学应用中显示出有希望的结果。磁性纳米粒子最有前途的应用之一是磁共振成像（MRI）。1，2磁性纳米颗粒对周围区域的T2弛豫时间具有缩短作用，这在MR图像中给出了负对比度。3药物递送和基因递送是通过将治疗剂递送到特定位置来实现有效治疗的其他有前景的应用。4.5在磁场梯度下施加在磁性纳米颗粒上的磁力有助于
Nanomedicine has received considerable attention in recent years. With an emergence of nanotechnology, nanomaterials with various functionalities have been developed for nanomedicine applications. Among those nanomaterials, magnetic nanoparticles have shown promising results in a wide range of biomedical applications due to their unique magnetic properties. One of the most promising applications of magnetic nanoparticles is Magnetic resonance imaging (MRI). 1, 2 Magnetic nanoparticles have a shortening effect on the T2 relaxation time of surrounding areas, which gives negative contrast in MR images. 3 Drug delivery and gene delivery are other promising applications that enable efficient treatment by delivering therapeutic agent to a specific location. 4, 5 A magnetic force exerted on magnetic nanoparticles under a magnetic field gradient helps