Bone lead content assessed by L-line x-ray fluorescence in lead-exposed and non-lead-exposed suburban populations in the United States.
Bone lead content assessed by L-line x-ray fluorescence in lead-exposed and non-lead-exposed suburban populations in the United States.
复制标题
通过 L 线 X 射线荧光评估美国铅暴露和非铅暴露郊区人群的骨铅含量。
DOI:
10.1073/pnas.90.7.2789
复制
发表时间:
1993
影响因子:
11.1
通讯作者:
Grainger,S
中科院分区:
文献类型:
--
作者:
Rosen,JF;Crocetti,AF;Balbi,K;Balbi,J;Bailey,C;Clemente,I;Redkey,N;Grainger,S
Measurements of lead (Pb) in bone reflect cumulative Pb exposure, whereas blood Pb levels are indices of absorption during the previous 21-30 days. This study was undertaken to estimate bone Pb concentrations by L-line x-ray fluorescence (LXRF) in a United States suburban population which was exposed to unusually high levels of Pb in emissions from an adjacent factory during 1963-1981, compared with concentrations similarly estimated in a matched suburban community without unusual Pb exposure. The mean bone Pb value in 269 residents of the highly exposed suburb (15 ppm) was 3-fold greater than that of the reference suburb (5 ppm). LXRF estimates of bone Pb identified those individuals at risk for adverse effects of Pb, whereas blood Pb levels were uninformative. Average LXRF-estimated bone Pb concentrations in residents of the unusually exposed suburb approximated estimated values in workers at Pb-processing factories.