Association of depression and its relation with complications in newly diagnosed type 2 diabetes.
Association of depression and its relation with complications in newly diagnosed type 2 diabetes.
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DOI：
10.4103/2230-8210.100670
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发表时间：
2012-09-01
影响因子：
--
通讯作者：
Singh, Vineet K
中科院分区：
文献类型：
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作者：
Bajaj, Sarita;Agarwal, Shalabh Kumar;Singh, Vineet K
导读：与普通人群相比，糖尿病患者的重度抑郁症患病率更高。这些关联可能与糖尿病患者抑郁症状的风险增加有关，与抑郁症状的2型糖尿病（T2DM）风险增加有关，或两者兼而有之。目的：研究北方邦东部地区新诊断的2型糖尿病患者抑郁与糖尿病及其并发症的关系。材料和方法：对60例患者和同等数量的年龄和性别匹配的对照组进行抑郁、糖尿病并发症和人口统计资料的评估。结果：抑郁症26例（43.34%），对照组8例（13.33%）（P = 0.002）。通过空腹和餐后血糖（FBG和PPBG）值测量，抑郁与出现时的高血糖水平相关。糖尿病肾病的存在与抑郁症显著相关，而其他糖尿病并发症（视网膜病变和血脂异常）的患病率虽然在抑郁症患者中较高，但没有统计学意义。糖尿病抑郁组HbA1c水平为8.56±1.66，非抑郁组为8.04±1.88 （P = 0.26）。结论：在我们的亚人群中，新诊断的2型糖尿病患者中抑郁症与糖尿病及其并发症的关联得到了强调，并强调了综合卫生服务的必要性。与对照组相比，他们中抑郁症的患病率更高。随着糖尿病并发症的恶化，患抑郁症的几率也在增加。
INTRODUCTION: The prevalence of major depressive disorders is higher among persons with diabetes compared to the general population. These associations may be related to the increased risk of depressive symptoms in individuals with diabetes, increased risk of type 2 diabetes (T2DM) in individuals with depressive symptoms, or both.OBJECTIVES: To study the association of depression with diabetes and its complications in newly diagnosed type 2 diabetes in eastern UP.MATERIAL AND METHODS: Sixty cases and an equal number of age- and sex-matched controls were assessed for depression, diabetes complications, and a demography profile.RESULTS: Depression was found in 26 (43.34%) cases, while it was present in only eight (13.33%) controls (P = 0.002). Depression correlated with the level of hyperglycemia at presentation, as measured by fasting and postprandial blood glucose (FBG and PPBG) values. The presence of diabetic nephropathy was significantly associated with depression, while the prevalence of other complications of diabetes (retinopathy and dyslipidemia), although higher among those with depression, was not statistically significant. The level of HbA1c was 8.56 ± 1.66 in the depressed versus 8.04 ± 1.88 in the non-depressed diabetics (P = 0.26).CONCLUSIONS: The association of depression with diabetes and its complications in newly diagnosed type 2 diabetics was highlighted in our subpopulation and emphasized the need for integrated health services. The prevalence of depression was higher among them compared to controls. The chances of becoming depressed increased as the diabetes complications worsened.