Investigation of the tuber constituents of maca (Lepidium meyenii Walp)
Investigation of the tuber constituents of maca (Lepidium meyenii Walp)
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DOI：
10.1021/jf020280x
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发表时间：
2002-09-25
影响因子：
6.1
通讯作者：
Pizza, C
中科院分区：
文献类型：
--
作者：
Piacente, S;Carbone, V;Pizza, C
在南美被称为玛卡，作为一种强大的提神剂而受到全世界的关注。由于这些报道，我们研究了玛卡块茎的次级代谢产物。玛卡块茎的甲醇提取物中除了含有游离糖和氨基酸外，还含有苹果酸及其苯甲酰衍生物，以及硫代葡萄糖苷。由于硫代葡萄糖苷及其衍生物因其生物活性而受到越来越多的关注，因此我们也对其己烷提取物中硫代葡萄糖苷降解产物的发生情况进行了研究，并分离出了苯基异硫氰酸酯及其间甲氧基衍生物。玛卡块茎甲醇提取物中还含有（1R,3S） 1甲基四氢β -碳-3-羧酸，这是一种据报道对中枢神经系统具有多种活性的分子。
Lepidium meyenii, known in South America as maca, has received attention worldwide as a powerful energizer that improves physical and mental conditions and increases fertility Because of these reports, we investigated the secondary metabolites of the tuber of maca The methanol extract of the tuber of maca contained, in addition to free sugars and amino acids the following undine, malic acid and its benzoyl derivative, and the glucosinolates, glucotropaeolin and m-methoxyglucotropaeolin Because glucosinolates and their derived products have received increasing attention due to their biological activities, the occurrence of glucosinolate degradation products in the hexane extract was also investigated, and benzylisothiocyanate and its m-methoxy derivative were isolated The two glucosinolates were semiquantified by HPLC, and benzylisothiocyanate was semiquantified by GC/MS The methanol extract of maca tuber also contained (1R,3S) 1 methyltetrahydro beta carboline-3-carboxylic acid a molecule which is reported to exert many activities on the central nervous system.