Comprehensive two-dimensional gas chromatography via differential flow modulation
Comprehensive two-dimensional gas chromatography via differential flow modulation
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DOI：
10.1021/ac000249z
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发表时间：
2000-09-15
影响因子：
7.4
通讯作者：
Hicks, CJ
中科院分区：
文献类型：
--
作者：
Seeley, JV;Kramp, F;Hicks, CJ
研制了一种新型的二维综合气相色谱仪。该技术使用6端口阀门从主柱收集流出物，并定期将流出物注入次级柱。二级柱的流量保持比主柱的流量大20倍，因此样品环的内容物可以在5%的收集时间内冲洗到二级柱中。当二次注入频率为1.0 Hz时，峰值宽度约为0.06 s。灵敏度不受影响，因为80%的样品通过两个柱并到达检测器。这种简单而有效的技术已被用于分析烷烃、烯烃、醛、醇、芳烃、酯和酮的混合物，具有高速和高分辨率。
A novel comprehensive two-dimensional gas chromatograph has been developed that utilizes differential non modulation. This technique uses a 6-port valve to collect effluent from a primary column and periodically inject the effluent into a secondary column. The flow in the secondary column is kept 20 times larger than the flow in the primary column so the contents of the sample loop can be flushed into the secondary column in 5% of the collection time. Peaks widths at half-maximum of approximately 0.06 s are generated for a 1.0 Hz secondary injection frequency. Sensitivity is not compromised, as 80% of the sample passes through both columns and reaches the detector. This simple yet effective technique has been used to analyze mixtures of alkanes, alkenes, aldehydes, alcohols, aromatics, esters, and ketones with high speed and high resolution.