1985 LEA,DOUGLAS MEMORIAL LECTURE - HYPERTHERMIA IN THE TREATMENT OF CANCER
1985 LEA,DOUGLAS MEMORIAL LECTURE - HYPERTHERMIA IN THE TREATMENT OF CANCER
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DOI：
10.1088/0031-9155/32/7/001
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发表时间：
1987-07-01
影响因子：
3.5
通讯作者：
FIELD, SB
中科院分区：
文献类型：
--
作者：
FIELD, SB
使用热疗治疗恶性疾病有充分的生物学理由。这篇综述包括对此基本原理的讨论，并描述了单独给予热疗或与电离辐射联合给予热疗对体外细胞、肿瘤或正常组织的影响。讨论的主题包括耐热性、降压敏化、分级、先前照射部位的再处理、热增强比和热剂量。考虑了热量传递和温度测量的问题，并简要说明了临床研究的现状。
There are sound biological reasons for using hyperthermia in the treatment of malignant disease. This review includes a discussion of this rationale and describes effects of hyperthermia either given alone or in combination with ionising radiation to cells in vitro, tumours or normal tissues. Topics discussed include thermotolerance, step-down sensitisation, fractionation, re-treatment of previously irradiated sites, thermal enhancement ratio and thermal dose. Problems of heat delivery and temperature measurement are considered and the current status of clinical studies is stated briefly.