Gene conversion and crossing over along the 405-kb left arm of Saccharomyces cerevisiae chromosome VII

Gene conversion and crossing over along the 405-kb left arm of Saccharomyces cerevisiae chromosome VII
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DOI:
10.1534/genetics.104.027961
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发表时间:
2004-09-01
期刊:
影响因子:
3.3
通讯作者:
Haber, JE
Haber, JE
中科院分区:
生物学2区
文献类型:
--
作者:
Malkova, A;Swanson, J;Haber, JE

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基因转换和交换进行了分析沿着10个间隔在405 kb的区域,几乎所有的左臂的染色体VII在酿酒酵母。交叉干扰检测到在所有的时间间隔,作为测量的数量减少的nonparental ditypes。我们已经评估了在相邻的间隔交叉之间的干扰的方法,保留在四分体中所包含的信息,而不是单一的分离。当交叉点附近区域的距离为
Gene conversions and crossing over were analyzed along 10 intervals in a 405-kb region comprising nearly all of the left arm of chromosome VII in Saccharomyces cerevisiae. Crossover interference was detected in all intervals as measured by a reduced number of nonparental ditypes. We have evaluated interference between crossovers in adjacent intervals by methods that retain the information contained in tetrads as opposed to single segregarns. Interference was seen between intervals when the distance in the region adjacent to a crossover was