Correlates of depressive symptoms among women undergoing the menopausal transition
Correlates of depressive symptoms among women undergoing the menopausal transition
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DOI：
10.1016/j.jpsychores.2007.02.003
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发表时间：
2007-09-01
影响因子：
4.7
通讯作者：
Flaws, Jodi A.
中科院分区：
文献类型：
--
作者：
Gallicchio, Lisa;Schilling, Chrissy;Flaws, Jodi A.
目的：研究表明，大约25%的绝经期妇女会出现抑郁症状。这项研究的目的是检验更年期状态是否与中年女性的抑郁体验有关，评估哪些人口统计和健康习惯特征与绝经过渡期间经历的抑郁症状有关，并分析激素水平与抑郁症状之间的关系。方法：对634名年龄在45岁至54岁的女性进行社区抽样调查，对数据进行分析。每个参与者都完成了一份调查问卷，并提供了一份血液样本，用于通过酶联免疫吸附试验测量雌激素和雄激素浓度。采用流行病学研究中心抑郁量表(CES-D)评估抑郁症状。结果：在研究中，大约25%的女性出现了抑郁症状(CES-D和GT；=16)。数据显示，目前吸烟、很少或没有规律的体力活动、健康状况不佳以及报告更多的更年期症状与抑郁症状独立且显著相关。绝经状态和测量的激素水平与抑郁症状没有显著的独立相关性。结论：这些发现证实了中年女性抑郁症状的相对较高的患病率，并提示某些人口统计、健康习惯和更年期症状特征可能比绝经状况和激素水平更重要地与中年抑郁症状相关。(C)2007年，爱思唯尔公司出版。
Objective: Studies indicate that approximately 25% of women undergoing the menopausal transition experience depressive symptoms. The purpose of this study was to examine whether menopausal status was associated with the experiencing of depression among midlife women, to assess which demographic and health habit characteristics were associated with depressive symptoms experienced during the menopausal transition, and to analyze the associations between hormone levels and depressive symptoms. Methods: Data from a community-based sample of 634 women aged 45 to 54 years were analyzed. Each participant completed a questionnaire and provided a blood sample that was used to measure estrogen and androgen concentrations by enzyme-linked immunosorbent assay. Depressive symptoms were assessed using the Center for Epidemiologic Studies-Depression Scale (CES-D). Results: Approximately 25% of the women in the study were experiencing depressive symptoms (CES-D >= 16). The data showed that being a current smoker, having little/no regular physical activity, being in poor health, and reporting a greater number of menopausal symptoms were independently and significantly associated with depressive symptoms. Menopausal status and the measured hormone levels were not significant independent correlates of depressive symptoms. Conclusions: These findings confirm the relatively high prevalence of depressive symptoms among midlife women and suggest that certain demographic, health habit, and menopausal symptom characteristics may be more important correlates of depressive symptoms in midlife than menopausal status and hormone levels. (c) 2007 Published by Elsevier Inc.