Phomopsidone A, a novel depsidone metabolite from the mangrove endophytic fungus Phomopsis sp A123
Phomopsidone A, a novel depsidone metabolite from the mangrove endophytic fungus Phomopsis sp A123
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Phomopsidone A，一种来自红树林内生真菌 Phomopsis sp A123 的新型缩酚酸代谢物
DOI：
10.1016/j.fitote.2014.05.001
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发表时间：
2014-07-01
期刊：
影响因子：
3.4
通讯作者：
Shen, Yuemao
中科院分区：
文献类型：
--
作者：
Zhang, Wei;Xu, Liyan;Shen, Yuemao
从红树林内生真菌拟茎点霉（Phomopsis sp.）A123中分离得到一个新的含氧杂环丁烷单元的五环缩酚酮（phomopsidone A）（1）、已报道的Excelsione（又称phomopsidone）（2）和四个已知的异苯并呋喃酮（3-6）。通过1D和2D NMR光谱分析和高分辨质谱鉴定了它们的结构。生物活性测试表明，这些化合物具有细胞毒性，抗氧化和抗真菌活性。(C)2014爱思唯尔有限公司版权所有。
One novel pentacyclic depsidone containing an oxetane unit, phomopsidone A (1), together with the reported excelsione (also named as phomopsidone) (2), and four known isobenzofuranones (3-6) were isolated from the mangrove endophytic fungus Phomopsis sp. A123. Their structures were elucidated by 1D and 2D NMR spectroscopic analysis and high resolution mass spectrometry. The bioactivity assays showed that these compounds possess cytotoxic, antioxidant, and antifungal activities. (C) 2014 Elsevier B.V. All rights reserved.