Expanding the Genetic Code

Expanding the Genetic Code
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DOI:
10.1126/science.302.5645.584
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发表时间:
2003-10
期刊:
影响因子:
56.9
通讯作者:
Lei Wang
Lei Wang
中科院分区:
综合性期刊1区
文献类型:
--
作者:
Lei Wang

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Proteins, the molecules that carry out most of the functions required for life, are built from 20 genetically encoded amino acids In his essay that won the Amersham Biosciences and Science Prize for young scientists, [Lei Wang][1] describes how he engineered the bacteria Escherichia coli to make unnatural amino acids. The biosynthesis strategy mimics the way that the common 20 amino acids are encoded. These additional building blocks allow the design of proteins with new properties. [1]: http://www.sciencemag.org/cgi/content/full/302/5645/584