Learning disorders in epilepsy
Learning disorders in epilepsy
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DOI：
10.1111/j.1528-1167.2006.00681.x
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发表时间：
2006-01-01
期刊：
影响因子：
5.6
通讯作者：
Beghi, Ettore
中科院分区：
文献类型：
--
作者：
Beghi, Massimiliano;Cornaggia, Cesare Maria;Beghi, Ettore
学习障碍（LD）是指在智商正常的受试者中，影响学习成绩或日常生活活动（需要阅读、写作或数学能力）的障碍。一般人群中LD的患病率为2-10%，阅读障碍是最常见的亚型。癫痫是儿童期最常见的神经系统疾病之一，估计患病率为4-5/1，000。在大约三分之二的病例中，癫痫被认为是特发性或隐源性的。LD在癫痫患者中比在普通人群中更常见：据说约25%的癫痫患者患有LD。各种社会心理、药物相关和癫痫相关因素可能与癫痫LD相关。LD可以是永久性的，也可以是依赖于状态的。永久性LD由脑损伤和/或稳定的脑功能障碍引起。相反，状态依赖性LD是潜在可逆和可治疗的;它们由癫痫相关因素引起。如果允许持续很长一段时间，依赖于状态的LD可能成为永久性的。
Learning disorders (LD) are disorders interfering with academic performance or with daily living activities requiring reading, writing, or mathematical abilities in subjects with a normal intelligence quotient. The prevalence of LD in the general population has been found to be 2-10% and reading disorders are the most frequent subtype. Epilepsy is one of the commonest neurological disorders in childhood with an estimated prevalence in 4-5/1,000. Epilepsy is considered to be idiopathic or cryptogenic in approximately two-thirds of cases. LD are more common in people with epilepsy than in the general population: about 25% of patients with epilepsy are said to have LD. Various psychosocial, medication-related, and epilepsy-related factors may be associated with LD in epilepsy. LD can be either permanent or state-dependent. Permanent LD are caused by a brain lesion and/or a stable brain dysfunction. In contrast, state-dependent LD are potentially reversible and treatable; they are caused by epilepsy-related factors. If allowed to persist for a long period, a state-dependent LD may become permanent.