Performance in adolescents of the two Japanese serum creatinine based estimated glomerular filtration rate equations, for adults and paediatric patients: A study of the Japan Renal Biopsy Registry and Japan Kidney Disease Registry from 2007 to 2013
Performance in adolescents of the two Japanese serum creatinine based estimated glomerular filtration rate equations, for adults and paediatric patients: A study of the Japan Renal Biopsy Registry and Japan Kidney Disease Registry from 2007 to 2013
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DOI：
10.1111/nep.12982
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发表时间：
2017-06-01
期刊：
影响因子：
2.5
通讯作者：
Matsuo, Seiichi
中科院分区：
文献类型：
--
作者：
Uemura, Osamu;Yokoyama, Hitoshi;Matsuo, Seiichi
对于成人和儿科患者，有两种不同的基于日本血清肌酐的肾小球滤过率（eGFR）估计公式，两种公式均适用于18岁受试者。本研究评估了两个方程在评估18岁慢性肾脏病患者eGFR方面的相对准确性。对2007年至2013年期间在日本肾活检登记处或日本肾脏疾病登记处登记的3042例2- 20岁患者（1679例男性和1363例女性）进行了评价。计算并比较了儿童公式（Uemura公式）和成人公式（3变量日本公式）得出的eGFR值，尤其是18岁患者。在所有年龄段，尤其是在较年轻的年龄段，使用成人公式计算的eGFR显著高于儿童公式。这一发现也在18岁的青少年中观察到，
There are two different Japanese serum creatinine-based equations for estimated glomerular filtration rate (eGFR), for adults and paediatric patients, with both equations deemed applicable to 18-year-old subjects. This study assessed the relative accuracy of the two equations in assessing eGFR in patients aged 18years with chronic kidney disease. A total of 3042 patients (1679 males and 1363 females), aged 2-20years, who were registered in the Japan Renal Biopsy Registry or the Japan Kidney Disease Registry between 2007 and 2013 were evaluated. eGFR values derived from formulas for children (Uemura's formula) and adults (the 3-variable Japanese formula) were calculated and compared, especially in patients aged 18years. At all ages, but especially at younger ages, eGFR was significantly higher when calculated with the adult than the paediatric formula. This finding was also observed in 18-year-old adolescents with eGFR