Strand invasion of conventional PNA to arbitrary sequence in DNA assisted by single-stranded DNA binding protein

Strand invasion of conventional PNA to arbitrary sequence in DNA assisted by single-stranded DNA binding protein
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DOI:
10.1039/b813975j
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发表时间:
2009-01-01
影响因子:
4.9
通讯作者:
Komiyama, Makoto
Komiyama, Makoto
中科院分区:
化学2区
文献类型:
--
作者:
Ishizuka, Takumi;Otani, Kosuke;Komiyama, Makoto

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在存在单链 DNA 结合蛋白 (SSB) 的情况下,无需化学修饰的常规肽核酸 (PNA)。阳离子有效地侵入 DNA 中的任意序列。
In the presence of single-stranded DNA binding protein (SSB), conventional peptide nucleic acid (PNA) without chemical modi. cations efficiently invades into arbitrary sequences in DNA.