The Impact of Exercise Training on Conduit Artery Wall Thickness and Remodeling in Chronic Heart Failure Patients

The Impact of Exercise Training on Conduit Artery Wall Thickness and Remodeling in Chronic Heart Failure Patients
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DOI:
10.1161/hypertensionaha.110.163022
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发表时间:
2011-01-01
期刊:
影响因子:
8.3
通讯作者:
Green, Daniel J.
Green, Daniel J.
中科院分区:
医学1区
文献类型:
--
作者:
Maiorana, Andrew J.;Naylor, Louise H.;Green, Daniel J.

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运动训练是慢性心力衰竭药物治疗的重要辅助手段,但运动对导管动脉重塑的影响程度尚不清楚。本研究的目的是评估有氧和阻力运动训练方式对慢性心力衰竭患者动脉重塑的影响。我们将36名未经训练的慢性心力衰竭患者随机分为抗阻训练组(58.8 +/- 3.5年)、有氧训练组(61.3 +/- 2.8年)和未经训练的对照组(64.4 +/- 2.4年)。12周后,阻力训练和有氧训练的峰值耗氧量均有所增加
Exercise training is an important adjunct to medical therapy in chronic heart failure, but the extent to which exercise impacts on conduit artery remodeling is unknown. The aim of this study was to evaluate the impact of aerobic and resistance exercise training modalities on arterial remodeling in patients with chronic heart failure. We randomized 36 untrained subjects with chronic heart failure to resistance training (58.8 +/- 3.5 years), aerobic training (61.3 +/- 2.8 years), or an untrained control group (64.4 +/- 2.4 years). Peak oxygen consumption during cycle ergometry increased after 12 weeks in both the resistance and aerobic training (P