First coincidences in pre-clinical Compton camera prototype for medical imaging
First coincidences in pre-clinical Compton camera prototype for medical imaging
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用于医学成像的临床前康普顿相机原型的首次巧合
DOI：
10.1016/j.nima.2004.06.014
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发表时间：
2004
影响因子：
1.4
通讯作者：
D. Žontar
中科院分区：
文献类型：
--
作者：
A. Studen;D. Burdette;E. Chesi;V. Cindro;N. Clinthorne;W. Duliński;J. Fuster;Li Han;H. Kagan;C. Lacasta;G. Llosá;A. C. Marques;N. Malakhov;D. Meier;M. Mikuž;S. Park;S. Roe;W. Rogers;J. Steinberg;P. Weilhammer;S. Wilderman;L. Zhang;D. Žontar
康普顿准直成像可以改善对由单光子发射计算机断层摄影（SPECT）中使用的放射性同位素发射的伽马射线的检测。我们提出了一个粗糙的原型，包括一个500 μm厚，256垫硅探测器与垫大小为1.4×1.4 mm2，结合15×15×1 cm 3碘化钠闪烁晶体耦合到一组20光电倍增器。重点放在硅探测器和相关的读出电子，这已被证明是迄今为止最具挑战性的部分设置的性能。使用VATAGP 3，128通道低噪声自触发ASIC作为硅探测器的前端获得了结果。光谱输出的噪声分布（σ）给出了等效噪声电荷（ENC），其平均值为137 e，扩展为10 e，对应于散射电子能量的1.15 keV FWHM的能量分辨率。触发器的稳定操作需要高于8.2 keV的阈值设置。在这两个模块中观测到符合的康普顿散射事件的光子发射的57 Co源的主要γ射线能量为122和136 keV。
Compton collimated imaging may improve the detection of gamma rays emitted by radioisotopes used in single photon emission computed tomography (SPECT). We present a crude prototype consisting of a single 500 μm thick, 256 pad silicon detector with pad size of 1.4×1.4 mm2, combined with a 15×15×1 cm3NaI scintillator crystal coupled to a set of 20 photo multipliers. Emphasis is placed on the performance of the silicon detector and the associated read-out electronics, which has so far proved to be the most challenging part of the set-up. Results were obtained using the VATAGP3, 128 channel low-noise self-triggering ASIC as the silicon detector's front-end. The noise distribution (σ) of the spectroscopic outputs gave an equivalent noise charge (ENC) with a mean value of 〈σ〉=137 e with a spread of 10 e , corresponding to an energy resolution of 1.15 keV FWHM for the scattered electron energy. Threshold settings above 8.2 keV were required for stable operation of the trigger. Coincident Compton scatter events in both modules were observed for photons emitted by57Co source with principal gamma ray energies of 122 and 136 keV .