Detection of local lung air content by electrical impedance tomography compared with electron beam CT
Detection of local lung air content by electrical impedance tomography compared with electron beam CT
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DOI：
10.1152/japplphysiol.00081.2002
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发表时间：
2002-08-01
影响因子：
3.3
通讯作者：
Hellige, G
中科院分区：
文献类型：
--
作者：
Frerichs, I;Hinz, J;Hellige, G
该研究的目的是通过将 EIT 结果与相同稳态条件下获得的电子束计算机断层扫描 (EBCT) 扫描进行比较，验证电阻抗断层扫描 (EIT) 检测因呼吸机设置修改而导致的空气含量局部变化的能力。实验在六只麻醉的仰卧猪上进行，这些猪在三个呼气末正压 (PEEP) 水平下以五个潮气量 (VT) 进行通气。通过 EIT（Goe-MF1 系统）和 EBCT（Imatron C-150XP 扫描仪）确定位于每个肺的腹侧、中部和背侧区域的六个感兴趣区域的肺空气含量变化，相对于最低 VT 和 PEEP 下的参考空气含量，作为局部电阻抗或肺组织密度的变化。在所有研究区域，两种方法均发现 VT 和 PEEP 导致局部空气含量增加。 EIT 和 EBCT 测定的肺空气含量变化之间存在良好的相关性。腹侧、中部和背侧区域的平均相关系数分别为0.81、0.87和0.93。该研究证实，EIT 是一种合适的非侵入性方法，用于检测空气含量的区域变化和监测人工通气的局部影响。
The aim of the study was to validate the ability of electrical impedance tomography (EIT) to detect local changes in air content, resulting from modified ventilator settings, by comparing EIT findings with electron beam computed tomography (EBCT) scans obtained under identical steady-state conditions. The experiments were carried out on six anesthetized supine pigs ventilated with five tidal volumes (VT) at three positive end-expiratory pressure (PEEP) levels. The lung air content changes were determined both by EIT (Goe-MF1 system) and EBCT (Imatron C-150XP scanner) in six regions of interest, located in the ventral, middle, and dorsal areas of each lung, with respect to the reference air content at the lowest VT and PEEP, as a change in either local electrical impedance or lung tissue density. An increase in local air content with VT and PEEP was identified by both methods at all regions studied. A good correlation between the changes in lung air content determined by EIT and EBCT was revealed. Mean correlation coefficients in the ventral, middle, and dorsal regions were 0.81, 0.87, and 0.93, respectively. The study confirms that EIT is a suitable, noninvasive method for detecting regional changes in air content and monitoring local effects of artificial ventilation.