Major alterations in body fluid status and blood rheology.
Major alterations in body fluid status and blood rheology.
复制标题
体液状态和血液流变学的主要改变。
DOI：
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发表时间：
2002
影响因子：
2.1
通讯作者：
V. Levin
中科院分区：
文献类型：
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作者：
I. Tikhomirova;A. Muravyov;V. Levin
由于脱水会导致身体水分的流失，我们研究了缺水过程中血液的流变学特性。本实验选用雄性白色大鼠64只，分为4组：对照组（n=19），实验组（n = 15）分别进行禁水3d、6d和10d。所获得的结果表明，在脱水条件下，动物的血液和血浆粘度以及红细胞聚集指数高于对照组。脱水3天后，这些变化是由于血管内水的损失。10天的禁水导致血液成分的显著紊乱以及红细胞膜性质的变化，而血液和血浆体积恢复到对照值。
Since the dehydration causes a loss of body water, we studied the rheological properties of blood in the course of water deprivation. Subjects used in this study were 64 white male rats divided into 4 groups: control (n=19) and 3 experimental groups which underwent water deprivation for 3 days (n=15), 6 days (n=15) and 10 days (n=15). The results obtained indicate that under dehydration animals have higher blood and plasma viscosity and erythrocyte aggregation index than in the control group. After 3 days of dehydration these changes are due to the loss of intravascular water. The water deprivation for 10 days causes significant disturbances in blood composition as well as changes of red blood cell membrane properties whereas blood and plasma volume return to control values.