An asymptomatic case of pulmonary cryptococcosis with endobronchial polypoid lesions and bilateral infiltrative shadow
An asymptomatic case of pulmonary cryptococcosis with endobronchial polypoid lesions and bilateral infiltrative shadow
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DOI：
10.1007/s10156-008-0617-0
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发表时间：
2008-08-01
影响因子：
2.2
通讯作者：
Oka, Mikio
中科院分区：
文献类型：
--
作者：
Shimizu, Hiroki;Miyashita, Naoyuki;Oka, Mikio
本文报告一例肺隐球菌病合并局灶性支气管息肉样病变。一位64岁的女性到我院求诊，希望进一步评估胸片上的异常阴影。她曾因类风湿性关节炎而服用皮质类固醇。胸部X线片显示右下和左中下肺野浸润性阴影，胸部计算机断层扫描（CT）显示双侧空域实变和多发结节。支气管镜检查结果显示左下叶后基底支气管开口处有白色息肉样病变。经支气管活检标本的组织学检查显示隐球菌微生物。经氟康唑治疗4个月后，浸润范围缩小，支气管息肉样病变消失。
A case of pulmonary cryptococcosis with focal endobronchial polypoid lesions is described. A 64-year-old woman consulted our hospital for further evaluation of an abnormal shadow on a chest radiograph. She had been prescribed corticosteroid for rheumatoid arthritis. Chest radiographs revealed an infiltrative shadow in the right lower and left middle and lower lung fields, and chest computed tomography (CT) revealed bilateral airspace consolidations and multiple nodules. A bronchoscopic finding revealed white polypoid lesions at the orifice of the posterior basal bronchus in the left lower lobe. Histopathological examination of transbronchial biopsy specimens demonstrated cryptococcal organisms. After fluconazole therapy for 4 months, the infiltrate had decreased in size and the bronchial polypoid lesions had disappeared.