A novel computational approach to simulate microswimmers propelled by bacterial flagella
A novel computational approach to simulate microswimmers propelled by bacterial flagella
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DOI：
10.1063/5.0069343
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发表时间：
2021-11-01
影响因子：
4.6
通讯作者：
Lim, Sookkyung
中科院分区：
文献类型：
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作者：
Lee, Wanho;Kim, Yongsam;Lim, Sookkyung
围毛鞭毛细菌通过嵌入细胞膜的旋转马达并因此旋转多个螺旋鞭毛而在流体环境中游动。我们提出了一个新的数学模型的microswimmer，可以自由运行，由鞭毛束和电机反转后翻滚推进。我们的细胞模型是由一个杆状的刚性细胞体和多个鞭毛随机分布在细胞体。这些鞭毛可以经历多态性转化。我们表明，鞭毛捆绑的影响鞭毛分布，因此鞭毛的数量。此外，细胞的重新定向受到鞭毛数量、细胞内有多少鞭毛改变其多态性、翻转时间、多态性序列的不同组合和随机运动逆转的影响。我们的数学方法可以应用于许多类型的微生物，并可能有助于了解其特征游泳机制。
Peritrichously flagellated bacteria swim in a fluid environment by rotating motors embedded in the cell membrane and consequently rotating multiple helical flagella. We present a novel mathematical model of a microswimmer that can freely run propelled by a flagellar bundle and tumble upon motor reversals. Our cell model is composed of a rod-shaped rigid cell body and multiple flagella randomly distributed over the cell body. These flagella can go through polymorphic transformations. We demonstrate that flagellar bundling is influenced by flagellar distribution and hence the number of flagella. Moreover, the reorientation of cells is affected by the number of flagella, how many flagella change their polymorphisms within a cell, the tumble timing, different combinations of polymorphic sequences, and random motor reversals. Our mathematical method can be applied to numerous types of microorganisms and may help to understand their characteristic swimming mechanisms.