The diagnostic value of tumor markers in bronchoalveolar lavage fluid for the peripheral pulmonary carcinoma

The diagnostic value of tumor markers in bronchoalveolar lavage fluid for the peripheral pulmonary carcinoma
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DOI:
10.1111/crj.12362
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发表时间:
2017-07-01
影响因子:
1.7
通讯作者:
Wu, Xue-ling
Wu, Xue-ling
中科院分区:
医学4区
文献类型:
--
作者:
Zhang, Shi;Zhao, Yun-feng;Wu, Xue-ling

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背景:探讨支气管肺泡灌洗液(BALF)及血清中泛素特异性肽酶8 (USP8)、几丁质酶3样1 (YKL40)、热休克蛋白90a (HSP90)、谷胱甘肽s转移酶P1 (GSTP1)、癌胚抗原(CEA)、神经元特异性烯醇酶(NSE)、细胞角蛋白片段抗原21-1 (CYFRA21-1)对周围性肺癌患者的诊断价值。方法采用酶联免疫吸附法测定50例周围性肺癌患者和50例肺部良性疾病患者血清中这些标志物的浓度。结果外周性肺癌组与良性肺疾病组比较差异有统计学意义(P
BackgroundTo investigate the value of Ubiquitin specific peptidase 8 (USP8), Chitinase 3-like 1 (YKL40), Heat shock protein 90a (HSP90), glutathione S-transferase P1 (GSTP1), carcinoembryonic antigen (CEA), neuron specific enolase (NSE) and cytokeratin fragment antiogen 21-1 (CYFRA21-1) in bronchoalveolar lavage fluid (BALF) and serum for diagnosis in patients with peripheral lung cancer.MethodsThe concentration of these markers were measured in 50 patients with peripheral lung cancer and 50 patients with benign lung diseases by using enzyme-linked immuno sorbent assay methods.ResultsThere were significant differences between the peripheral lung cancer group and the benign lung disease group (P