Fetal growth: a review of terms, concepts and issues relevant to obstetrics

Fetal growth: a review of terms, concepts and issues relevant to obstetrics
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DOI:
10.1002/uog.11204
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发表时间:
2013-02-01
影响因子:
7.1
通讯作者:
Joseph, K. S.
Joseph, K. S.
中科院分区:
医学1区
文献类型:
--
作者:
Mayer, C.;Joseph, K. S.

文献摘要

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围产期文献包括几个潜在的混乱和有争议的术语和概念有关的胎儿大小和生长。本文从产科角度讨论胎儿生长,并讨论各种问题,包括决定胎儿生长轨迹的生理机制,胎儿生长异常的已知危险因素,与胎儿生长受限和过度生长相关的诊断和预后问题以及胎儿生长的时间趋势。还讨论了胎儿生长标准和胎儿生长参考之间的区别,以及基于估计胎儿体重的胎儿生长图表与基于出生体重的胎儿生长图表之间的区别。讨论的其他概念包括妊娠期胎儿生长受限的发生率(胎儿生长受限的频率随着妊娠期的增加而增加还是减少?),研究表明胎儿生长与成人慢性疾病(如冠心病)之间存在关联,这对产科有重要意义,需要定制胎儿生长标准。
The perinatal literature includes several potentially confusing and controversial terms and concepts related to fetal size and growth. This article discusses fetal growth from an obstetric perspective and addresses various issues including the physiologic mechanisms that determine fetal growth trajectories, known risk factors for abnormal fetal growth, diagnostic and prognostic issues related to restricted and excessive growth and temporal trends in fetal growth. Also addressed are distinctions between fetal growth standards' and fetal growth references', and between fetal growth charts based on estimated fetal weight vs those based on birth weight. Other concepts discussed include the incidence of fetal growth restriction in pregnancy (does the frequency of fetal growth restriction increase or decrease with increasing gestation?), the obstetric implications of studies showing associations between fetal growth and adult chronic illnesses (such as coronary heart disease) and the need for customizing fetal growth standards.