Gamete and immune cell recognition revisited.

Gamete and immune cell recognition revisited.
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重新审视配子和免疫细胞识别。

DOI:
10.1002/bies.950171212
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发表时间:
1995
期刊:
BioEssays : news and reviews in molecular, cellular and developmental biology.
影响因子:
--
通讯作者:
Foltz,KR
Foltz,KR
中科院分区:
--
文献类型:
--
作者:
BeltonJr,RJ;Foltz,KR

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Fertilization is the result of a series of successful recognition and binding events mediated by gamete surface molecules. Recent advances in the identification and characterization of some of these recognition molecules provide extremely valuable information necessary to understand sperm‐egg recognition and subsequent egg activation. We discuss these new data in the context of the model of gamete recognition first proposed by F.R. Lillie in the early part of the 20th century, and revisited periodically in the subsequent literature, which relates fortilization events to those of immune cell recognition and activation events. Here we discuss the principles underlying the molecular recognition and activation mechanisms of gametes and immune cells.
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