The noodle defense.
The noodle defense.
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面条防御。
DOI：
10.1083/jcb.201310128
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发表时间：
2013
期刊：
影响因子：
--
通讯作者：
Swanson,JoelA
中科院分区：
文献类型：
--
作者：
Swanson,JoelA
Macrophages ingest and kill microbes by phagocytosis and delivery to lysosomes. In this issue, Prashar et al. (2013, J. Cell Biol. http://dx.doi.org/10.1083/jcb.201304095) demonstrate that the elongated morphology of filamentous bacteria does not prevent ingestion by macrophages or the fusion of lysosomes, but creates a chimeric, unclosed phagolysosomal compartment whose leakiness blunts the toxicity of lysosomal enzymes, thereby increasing bacterial survival.
