Stereocontrolled conversion of secondary benzyl ether tricarbonylchromium(0) complexes into tertiary benzyl ether complexes
Stereocontrolled conversion of secondary benzyl ether tricarbonylchromium(0) complexes into tertiary benzyl ether complexes
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仲苄基醚三羰基铬(0)络合物立体控制转化为叔苄基醚络合物
DOI：
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发表时间：
1996
期刊：
影响因子：
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通讯作者：
Mark H. Smith
中科院分区：
文献类型：
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作者：
Susan E. Gibson (née Thomas);P. C. V. Potter;Mark H. Smith
叔丁基锂与对映体富集的仲苯醚三羰基铬(0)配合物（96-99% ee）脱质子，然后用一系列亲电试剂猝灭，得到高对映体纯度（92-98.5% ee）的叔苯醚三羰基铬(0)配合物，产率高（65-94%），总体构型保持不变。
Deprotonation of enantiomerically enriched secondary benzyl ether tricarbonylchromium(0) complexes (96–99% ee) with tert-butyllithium followed by quenching with a range of electrophiles gives tertiary benzyl ether tricarbonylchromium(0) complexes of high enantiomeric purity (92–98.5% ee) in good yield (65–94%) with overall retention of configuration.