Corneal thickness in children
Corneal thickness in children
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DOI：
10.1016/j.ajo.2004.06.030
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发表时间：
2004-11-01
影响因子：
4.2
通讯作者：
Wilhelmus, KR
中科院分区：
文献类型：
--
作者：
Hussein, MAW;Paysse, EA;Wilhelmus, KR
目的：为了确定正常的中央和中央旁角膜厚度测量在儿科人群，并确定这些测量是否是一致的，在不同的儿科年龄组和不同的种族groups.DESIGN：前瞻性观察casesseries.METHODS：角膜厚度测量进行了198眼108名儿童。在中心以及距角膜中心3 mm的4个旁中心部位的3、6、9和12点钟位置进行测量。双尾t检验用于比较角膜厚度值的连续平均值。方差分析（ANOVA）进行，以确定，年龄和种族groups.RESULTS之间的差异：平均中央角膜厚度（CCT）为549 +/- 46妈妈。距角膜中心3 mm处测量的中央旁角膜厚度平均值如下：上级，575 +/- 52 mum;鼻侧，568 +/- 50 mum;下侧，568 +/- 51 mum;颞侧，574 +/- 47 mum。平均CCT值显著小于每个平均旁中心点（每次比较P <0.05，配对t检验）。中央旁角膜厚度测量显示不同位置之间无显著差异（P > 0.05，方差分析）。每个年龄组的平均CCT +/- SD如下：6至23个月，538 +/- 40 mum; 2至4岁，546 +/- 41 mum; 5至9岁，566 +/- 48 mum; 10至18岁，554 +/- 35 mum（ANOVA P = .012）。ANOVA进行中央角膜厚度测量值显示种族subgroup.CONCLUSIONS：小儿中央和旁中央角膜厚度随着时间的推移缓慢增加，并达到成人厚度在5至9岁之间没有显着差异。(C)2004年，Elsevier Inc. All rights reserved.
OBJECTIVE: To determine normal central and paracentral corneal thickness measurements in the pediatric population and to determine if these measurements are consistent across different pediatric age groups and different racial groups.DESIGN: Prospective observational case series.METHODS: Pachymetry measurements were performed on 198 eyes of 108 children. The measurements were taken centrally as well as at four paracentral sites 3 nun from the corneal center at the 3, 6, 9, and 12 o'clock positions. The two-tailed t test was used for comparison of the continuous means for values of corneal thickness. Analysis of variance (ANOVA) was performed to deter, mine differences among age and ethnic groups.RESULTS: The mean central corneal thickness (CCT) was 549 +/- 46 mum. Paracentral corneal thickness mean values, as measured 3 mm from the corneal center, were as follows: superior, 575 +/- 52 mum; nasal, 568 +/- 50 mum; inferior, 568 +/- 51 mum; and temporal, 574 +/- 47 mum. The mean CCT values were significantly thinner than at each of the mean paracentral points (P < .05 for each comparison, paired t test). Paracentral corneal thickness measurements demonstrated no significant differences between locations (P > .05, variance analysis). The mean CCT +/- SD for each age group was as follows: 6 to 23 months, 538 +/- 40 mum; 2 to 4 years, 546 +/- 41 mum; 5 to 9 years, 566 +/- 48 mum; and 10 to 18 years, 554 +/- 35 mum (ANOVA P = .012). ANOVA performed on central pachymetry values demonstrated no significant differences among racial subgroups.CONCLUSIONS: Pediatric central and paracentral corneal thicknesses increase slowly over time and reach adult thicknesses at 5 to 9 years of age. (C) 2004 by Elsevier Inc. All rights reserved.