Factors associated with late presentation to HIV/AIDS care in South Wollo ZoneEthiopia: a case-control study.
Factors associated with late presentation to HIV/AIDS care in South Wollo ZoneEthiopia: a case-control study.
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DOI：
10.1186/1742-6405-8-8
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发表时间：
2011-02-28
影响因子：
2.2
通讯作者：
Deribe K
中科院分区：
文献类型：
--
作者：
Abaynew Y;Deribew A;Deribe K
撒哈拉以南非洲地区获得免费抗逆转录病毒治疗的机会一直在稳步增加。大规模抗逆转录病毒治疗计划的成功取决于艾滋病毒/艾滋病护理的早期启动。该研究的目的是检查与延迟接受艾滋病毒/艾滋病护理相关的因素。 2010年3月1日至31日，在埃塞俄比亚北部的Dessie转诊医院和Borumeda地区医院进行了一项病例对照研究。该研究共有 320 名研究参与者（160 名病例和 160 名对照）。病例是艾滋病毒/艾滋病 (PLHA) 感染者，他们在首次到抗逆转录病毒治疗 (ART) 诊所就诊时，世界卫生组织临床分期为 III 或 IV 期，或 CD4 淋巴细胞计数低于 200/uL。对照是 PLHA，他们在首次到医院 ART 诊所就诊时，具有 WHO I 或 II 期或 CD4 淋巴细胞计数为 200/uL 或更多，无论临床分期如何。病例和对照由训练有素的护士使用预先测试的结构化问卷进行访谈。对 10 名卫生工作者和 8 名感染者进行了深入访谈。与家人同住[OR = 3.29, 95% CI: 1.28-8.45)]、住在出租屋[OR = 2.52, 95% CI: 1.09-5.79]、非孕妇[OR = 9.3, 95% CI: 1.93-44.82]、认为ART有很多副作用的PLHA [OR = 6.23, 95% CI:1.63,23.82)]，他们认为 HIV 是一种耻辱性疾病 [OR = 3.1，95% CI：1.09-8.76]，他们进行了疾病/症状测试 [OR = 2.62，95% CI：1.26-5.44]，他们没有向伴侣透露自己的 HIV 状况 [OR = 2.78， 95% CI: 1.02-7.56]、经常饮酒 [OR = 3.55, 95% CI: 1.63-7.71] 以及在 HIV 诊断时与伴侣相处超过 120 个月 [OR = 5.86, 95% CI: 1.35-25.41] 与较晚接受 HIV/AIDS 护理显着相关。定性调查结果显示，认识不足、不公开、感知到的抗逆转录病毒治疗副作用和艾滋病毒耻辱是延迟接受艾滋病毒/艾滋病护理的主要障碍。加强艾滋病毒/艾滋病早期护理的努力应侧重于解决患者的担忧，例如耻辱、药物副作用和信息披露。
Access to free antiretroviral therapy in Sub-Saharan Africa has been steadily increasing. The success of large-scale antiretroviral therapy programs depends on early initiation of HIV/AIDs care. The purpose of the study was to examine factors associated with late presentation to HIV/AIDS care. A case-control study was conducted in Dessie referral and Borumeda district hospitals from March 1 to 31, 2010, northern Ethiopia. A total of 320 study participants (160 cases and 160 controls) were included in the study. Cases were people living with HIV/AIDS (PLHA) who had a WHO clinical stage of III or IV or a CD4 lymphocyte count of less than 200/uL at the time of the first presentation to antiretroviral treatment (ART) clinics. Controls were PLHA who had WHO stage I or II or a CD4 lymphocyte count of 200/uL or more irrespective of clinical staging at the time of first presentation to the ART clinics of the hospitals cases and controls were interviewed by trained nurses using a pre-tested and structured questionnaire. In-depth interviews were conducted with ten health workers and eight PLHA. PLHA who live with their families [OR = 3.29, 95%CI: 1.28-8.45)], lived in a rented house [OR = 2.52, 95%CI: 1.09-5.79], non-pregnant women [OR = 9.3, 95% CI: 1.93-44.82], who perceived ART have many side effects [OR = 6.23, 95%CI:1.63,23.82)], who perceived HIV as stigmatizing disease [OR = 3.1, 95% CI: 1.09-8.76], who tested with sickness/symptoms [OR = 2.62, 95% CI: 1.26-5.44], who did not disclose their HIV status for their partner [OR = 2.78, 95% CI: 1.02-7.56], frequent alcohol users [OR = 3.55, 95% CI: 1.63-7.71] and who spent more than 120 months with partner at HIV diagnosis[OR = 5.86, 95% CI: 1.35-25.41] were significantly associated with late presentation to HIV/AIDS care. The qualitative finding revealed low awareness, non-disclosure, perceived ART side effects and HIV stigma were the major barriers for late presentation to HIV/AIDS care. Efforts to increase early initiation of HIV/AIDS care should focus on addressing patient's concerns such as stigma, drug side effects and disclosure.
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影响因子：
4.9
作者：
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通讯作者：
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影响因子：
4.9
作者：
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Rosen S
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1.4
作者：
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通讯作者：
Lert, France