Clinical Predictors of Long-Term Outcomes in Patients With Critical Limb Ischemia Who have Undergone Endovascular Therapy
Clinical Predictors of Long-Term Outcomes in Patients With Critical Limb Ischemia Who have Undergone Endovascular Therapy
复制标题
接受血管内治疗的严重肢体缺血患者长期结果的临床预测因素
作者：
Shang;Yueh;Hsin;Tien;Chien;Shih;Hsuan
血管内治疗（EVT）治疗严重肢体缺血（CLI）患者的长期结局的临床预测因素尚不清楚。在这项研究中，研究了EVT治疗CLI患者长期结局的临床预测因素。在这项前瞻性、观察性研究中，我们分析了2005年至2012年间接受EVT的253例台湾CLI患者（314条肢体）。考克斯模型用于估计死亡、肢体缺失和持续临床成功（SCS）的风险比。多变量分析显示，年龄、房颤（AF）、终末期肾病（ESRD）和白蛋白是死亡率的重要预测因素。患有冠状动脉疾病和低白蛋白水平的患者具有重大肢体截肢的显著风险，而AF、ESRD和白蛋白是SCS的显著独立预测因子。除了先前报道的预测因子外，我们发现AF和营养不良可用于预测经EVT治疗的CLI患者的长期结局。
Clinical predictors of long-term outcomes in patients with critical limb ischemia (CLI) treated with endovascular therapy (EVT) remain unclear. In this study, clinical predictors of long-term outcomes in EVT-treated patients with CLI were investigated. In this prospective, observational study, we analyzed a total of 253 Taiwanese patients with CLI with 314 limbs who underwent EVT between 2005 and 2012. Cox models were used to estimate hazard ratios of death, limb loss, and sustained clinical success (SCS). Multivariate analysis showed that age, atrial fibrillation (AF), end-stage renal disease (ESRD), and albumin were significant predictors of mortality. Patients with coronary artery disease and low albumin levels had a significant risk of major limb amputation, while AF, ESRD, and albumin were significant, independent predictors of SCS. In addition to previously reported predictors, we showed that AF and malnutrition can be used to predict long-term outcome in EVT-treated patients with CLI.