Construction of Hypercycles in Typogenetics with Evolutionary Algorithms
Construction of Hypercycles in Typogenetics with Evolutionary Algorithms
复制标题
用进化算法构建类型遗传学中的超循环
DOI：
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发表时间：
2007
期刊：
影响因子：
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通讯作者：
K. Wee
中科院分区：
文献类型：
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作者：
Chohwa Gwak;K. Wee
超循环的概念是由M.Eigen和P.Schuster为研究生命起源问题而提出的。超循环是模拟非生物时期分子进化的一种简单的自我复制系统。类型遗传学是一个正式的字符串系统，最初由D.Hofstadter设计，用来解释计算和分子遗传学之间的联系。后来由H·莫里斯建立了一个研究人工生命的正式系统。进化算法是Kvesicka等人使用的。在排型遗传学中找到一个小的超循环。我们对他们的算法进行了改进，构造了许多大尺寸的超圈。我们还用不同长度的酶和酶与其功能之间的各种映射进行了实验。
The concept of hypercycles was proposed by M. Eigen and P. Schuster to study the origin-of-life problem. A hypercycle is a simple self-reproducing system modeling molecular evolution in the abiotic period. Typogenetics is a formal system of strings originally devised by D. Hofstadter to explain the connection between computation and molecular genetics. It was later established by H. Morris as a formal system to study artificial life. Evolutionary algorithms were used by Kvasnicka et al. to find a small hypercycle in typogenetics. We improve upon their algorithm and construct many hypercycles of large sizes. We also experimented with enzymes of different lengths and various mappings between enzymes and their functions.