AGE-RELATED-CHANGES IN SEBACEOUS WAX ESTER SECRETION RATES IN MEN AND WOMEN
AGE-RELATED-CHANGES IN SEBACEOUS WAX ESTER SECRETION RATES IN MEN AND WOMEN
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DOI：
10.1111/1523-1747.ep12277224
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发表时间：
1985-01-01
影响因子：
6.5
通讯作者：
DOWNING, DT
中科院分区：
文献类型：
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作者：
JACOBSEN, E;BILLINGS, JK;DOWNING, DT
测量了109名男性和167名女性（年龄在15-97岁之间）额头的可持续皮脂酯分泌率。每次测量都是在通过将脂质过夜吸收到膨润土粘土层中而首先耗尽皮肤皮脂储库之后进行的。然后将脂质吸收到新鲜粘土中3小时，其中嵌入两个2厘米的布盘。用乙醚从圆盘中提取吸收的脂质，并通过薄层色谱法分析蜡酯。对于男性和女性来说，在所有年龄段都有广泛的蜡酯分泌率。15至35岁年龄段的发病率最高，在整个成年年龄段似乎持续下降。值的日志（蜡酯）更好地与年龄比蜡酯分泌的未转换值的相关性。log（蜡酯）与年龄的最佳拟合方程表明，男性皮脂分泌每十年下降约23%，女性每十年下降约32%。
Sustainable rates of sebaceous was ester secretion were measured on the foreheads of 109 men and 167 women, aged 15-97. Each measurement was made after first depleting the cutaneous sebum reservoir by overnight absorption of lipid into a layer of bentonite clay. Lipid was then absorbed for 3 h into fresh clay in which two 2-cm cloth disks were embedded. The absorbed lipid was extracted from the disks with ether and analyzed for wax esters by thin-layer chromatography. For both men and women there was a wide range of wax ester secretion rates at all ages. Rates were highest in the 15- to 35-year-olds and appeared to decline continuously throughout the adult age range. Values of log(wax esters) were better correlated with age than the untransformed values of wax ester secretion. The equations of best fit of log(wax esters) vs age suggested that sebum secretion declines about 23% per decade in men and 32% per decade in women.