Role of capping agents in controlling silver nanoparticles size, antibacterial activity and potential application as optical hydrogen peroxide sensor
Role of capping agents in controlling silver nanoparticles size, antibacterial activity and potential application as optical hydrogen peroxide sensor
复制标题
DOI：
10.1039/c6ra03766f
复制
发表时间：
2016-01-01
期刊：
影响因子：
3.9
通讯作者：
Ahn, Chi Won
中科院分区：
文献类型：
--
作者：
Ajitha, B.;Reddy, Y. Ashok Kumar;Ahn, Chi Won
采用快速一锅化学还原法研究了不同封端剂对银纳米粒子（AgNPs）的影响。测试了四种封端剂：聚乙二醇（PEG）、乙二胺四乙酸（EDTA）、聚乙烯吡咯烷酮（PVP）和聚乙烯醇（PVA）。FTIR研究表明，所形成的AgNP被它们各自的封端剂适当地包封。结构和形态学研究证实了以下相对平均粒径：PEG-AgNP> EDTA-AgNP> PVP-AgNP> PVA-AgNP。光吸收和光致发光的研究表明，分别，更大的吸收蓝移和更大的发射强度为较小的加盖颗粒。PVA-AgNP的ζ电位分析显示-46.6mV的值，表明其高稳定性。因此，PVA-AgNP不仅被观察到是测试的AgNP中最小、最蓝移和最稳定的，而且它们显示出最高的抗菌活性。因此，PVA-AgNP被用作基于局域表面等离子体共振（LSPR）的H2 O2传感器，这很重要，因为H2 O2等活性氧物质的检测在医学和环境领域具有重要意义。基于PVA-AgNPs的传感器成功地检测了浓度低至10（-7）M的H2 O2。因此，使用这些纳米粒子的新生物传感器应该在各个领域找到有前途的机会。
The influence of capping agents on silver nanoparticles (AgNPs) was investigated through a rapid and single-pot chemical reduction method. Four capping agents were tested: polyethylene glycol (PEG), ethylenediaminetetraacetic acid (EDTA), polyvinyl pyrrolidone (PVP) and polyvinyl alcohol (PVA). FTIR studies demonstrated that the formed AgNPs were properly encapsulated by their respective capping agents. Structural and morphological studies confirmed the following relative average particle sizes: PEG-AgNPs > EDTA-AgNPs > PVP-AgNPs > PVA-AgNPs. Optical absorption and photoluminescence studies showed, respectively, a greater absorption blue shift and greater emission intensity for the smaller capped particles. Zeta potential analysis of the PVA-AgNPs showed a value of -46.6 mV, indicating their high stability. The PVA-AgNPs were thus not only observed to be the smallest, most blue-shifted and most stable of the tested AgNPs, but also they displayed the highest antibacterial activity. The PVA-AgNPs were therefore applied as a localized surface plasmon resonance (LSPR)-based H2O2 sensor, which is important because the detection of reactive oxygen species such as H2O2 is of significance in the medical and environmental fields. The sensor based on the PVA-AgNPs successfully detected H2O2 at concentrations as low as 10(-7) M. New biosensors using these NPs should thus find promising opportunities in a variety of fields.