ARTERIAL THROMBOSIS IN THE NEPHROTIC SYNDROME
ARTERIAL THROMBOSIS IN THE NEPHROTIC SYNDROME
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DOI：
10.1136/pgmj.70.830.905
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发表时间：
1994-12-01
影响因子：
5.1
通讯作者：
BELL, GM
中科院分区：
文献类型：
--
作者：
FAHAL, IH;MCCLELLAND, P;BELL, GM
血栓形成是肾病综合征患者发病和死亡的常见原因，静脉血栓并发症是公认的，但动脉并发症是罕见的。血栓形成是多因素的，并且归因于由于凝血和纤维蛋白溶解系统中涉及的各种因子的血液水平的改变、血小板功能的改变、静脉淤滞、血液浓缩、血液粘度增加以及可能的类固醇给药引起的高凝状态。血栓形成，特别是动脉血栓形成是肾病患者的一个重要的和潜在的严重问题。需要了解病情及其发病机制。需要对风险因素进行评估，以便采取适当的预防措施。
Thrombosis is a frequent cause of morbidity and mortality in patients with the nephrotic syndrome, Venous thrombotic complications are well recognized but arterial complications are rare. Thrombosis is multifactorial, and has been attributed to a hypercoaguable state due to alterations in blood levels of the various factors involved in the coagulation and fibrinolytic systems, alterations in platelet function, venous stasis, haemoconcentration, increased blood viscosity and possibly the administration of steroids. Thrombosis in general and arterial thrombosis in particular is a significant and potentially serious problem in nephrotic patients. Awareness of the condition and its pathogenesis is needed. Assessment for the risk factors is required to allow appropriate prophylactic measures to be taken.