The novel NOX inhibitor 2‐acetylphenothiazine impairs collagen‐dependent thrombus formation in a GPVI‐dependent manner
The novel NOX inhibitor 2‐acetylphenothiazine impairs collagen‐dependent thrombus formation in a GPVI‐dependent manner
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DOI：
10.1111/j.1476-5381.2012.02130.x
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发表时间：
2013-01
影响因子：
7.3
通讯作者：
D. Vara;M. Campanella;M. Campanella;G. Pula
中科院分区：
文献类型：
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作者：
D. Vara;M. Campanella;M. Campanella;G. Pula
NADPH氧化酶（NOX）通过一种很大程度上未知的机制促进血小板活化。在这里，我们研究了新型NOX抑制剂2-乙酰吩噻嗪（2-APT）对人血小板功能反应和细胞内信号通路的影响。
NADPH oxidases (NOXs) contribute to platelet activation by a largely unknown mechanism. Here, we studied the effect of the novel NOX inhibitor 2‐acetylphenothiazine (2‐APT) on human platelet functional responses and intracellular signaling pathways.