Primary aldosteronism diagnosed in a patient with severe renal disease.
Primary aldosteronism diagnosed in a patient with severe renal disease.
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一名患有严重肾脏疾病的患者被诊断为原发性醛固酮增多症。
DOI：
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发表时间：
2018
期刊：
影响因子：
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通讯作者：
M. K. Zouaghi
中科院分区：
文献类型：
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作者：
M. Hajji;L. Rais;R. Kheder;H. Jebali;L. Ben Fatma;M. K. Zouaghi
虽然最初认为是罕见的，原发性醛固酮增多症现在是继发性高血压的更常见的原因之一。根据较早的数据，最初估计原发性醛固酮增多症占所有高血压患者的不到1%。然而，随后的数据表明，它实际上可能发生在多达5-15%的高血压患者中。我们报告一位66岁有高血压病史的病人，在他发展为血管性肾病继发严重肾衰竭时，被诊断为原发性醛固酮增多症。本病例报告说明了原发性醛固酮增多症的诊断困难，并强调了延迟诊断对肾脏存活率和患者生活质量的影响。
Although initially considered a rarity, primary aldosteronism now is one of the more common causes of secondary hypertension. Based on older data, it was originally estimated that primary aldosteronism accounted for less than 1% of all patients with hypertension. Subsequent data, however, indicated that it may actually occur in as many as 5-15% of patients with hypertension. Here we present a 66-year-old patient with a history of hypertension who was diagnosed with primary hyperaldosteronism at the time he had developed a severe renal failure secondary to a vascular nephropathy. This case report illustrates the difficulties in diagnosis of primary hyperaldosteronism, and highlights the effects of the delay of diagnosis on renal survival and on patient quality of life.