Natural products as a source of Alzheimer's drug leads.

Natural products as a source of Alzheimer's drug leads.
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DOI:
10.1039/c0np00027b
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发表时间:
2011-01
影响因子:
11.9
通讯作者:
Howes MJ
Howes MJ
中科院分区:
化学1区
文献类型:
--
作者:
Williams P;Sorribas A;Howes MJ

文献摘要

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本综述重点关注使用天然产品治疗阿尔茨海默病的最新进展。化合物涵盖多种结构类别,并根据其作用机制进行组织,主要关注主要假设。总体而言,该综述讨论了 180 多种化合物并总结了 393 篇参考文献。
This review focuses on recent developments in the use of natural products as therapeutics for Alzheimer’s disease. Compounds span a diverse array of structural classes and are organized according to their mechanism of action, with the focus primarily on the major hypotheses. Overall, the review discusses more than 180 compounds and summarizes 393 references.