Neural Responses in the Retinotopic Representation of the Blind Spot in the Macaque V1 to Stimuli for Perceptual Filling-In
Neural Responses in the Retinotopic Representation of the Blind Spot in the Macaque V1 to Stimuli for Perceptual Filling-In
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DOI：
10.1523/jneurosci.20-24-09310.2000
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发表时间：
2000-12
期刊：
影响因子：
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通讯作者：
H. Komatsu;M. Kinoshita;I. Murakami
中科院分区：
文献类型：
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作者：
H. Komatsu;M. Kinoshita;I. Murakami
当覆盖整个盲点的视觉刺激被单眼呈现时，周围视野的颜色和亮度在盲点内被看到，尽管它没有接收视网膜输入。关于这种知觉填充的重要问题是，当填充发生时，视觉系统中代表盲点内视野位置的神经元是否被激活，如果是，这些神经元的特性是什么。为了解决这些问题，我们记录了清醒猴子初级视觉皮层（V1）中单个神经元的活动。我们首先确定了代表盲点区域的V1区域，然后评估了对各种大小的静止视觉刺激的神经反应。我们发现，在第4层和更深的层，特别是第6层，有神经元的反应，大的刺激覆盖盲点，诱导知觉填充。这些神经元中的大多数都有非常大的双眼感受野，延伸到盲点之外。这些神经元也喜欢相对较大的刺激，并表现出颜色选择性。这些结果表明，当一个大的均匀的表面上的盲点，在V1区的神经元代表的盲点传输信号必不可少的填充，告知存在一个大的表面，以及在盲点的小刺激的情况下。
When visual stimuli that cover the entire blind spot are presented monocularly, the color and brightness of the surrounding field are seen within the blind spot, although it receives no retinal input. Important questions about such perceptual filling-in are whether neurons in the visual system representing visual field locations within the blind spot are activated when filling-in occurs and, if so, what the properties of these neurons are. To address these questions, we recorded the activities of single neurons in the primary visual cortex (V1) of the awake monkey. We first identified the area of V1 representing the region of the blind spot and then assessed neural responses to stationary visual stimuli of various size. We found that there are neurons in layer 4 and deeper laminae, particularly layer 6, that respond to large stimuli covering the blind spot which induces perceptual filling-in. Most of these neurons had very large binocular receptive fields that extended outside the blind spot. These neurons also preferred relatively large stimuli and exhibited color selectivity. These results indicate that when a large uniform surface is presented on the blind spot, neurons at the V1 region representing the blind spot transmit signals essential for filling-in that inform of the presence of a large surface as well as the absence of smaller stimuli at the blind spot.