Validity of body mass index and waist circumference to detect excess fat mass in children aged 7-14 years
Validity of body mass index and waist circumference to detect excess fat mass in children aged 7-14 years
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DOI：
10.1038/ejcn.2010.245
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发表时间：
2011-02-01
影响因子：
4.7
通讯作者：
Kromeyer-Hauschild, K.
中科院分区：
文献类型：
--
作者：
Glaesser, N.;Zellner, K.;Kromeyer-Hauschild, K.
背景/目的：评价体重指数（BMI）和腰围（WC）对过度肥胖的筛查效果。此外，从不同的国际和国家参考系统的基础上BMI和WC的截断诊断准确性investigated. Subject/Methods：从2132耶拿7-14岁的儿童在2005/2006年进行的数据进行了分析。构建受试者工作特征（ROC）曲线以评估BMI和WC，作为过度肥胖（来自皮褶）的筛选指标。敏感性，特异性和阳性预测值（PPV）计算两个BMI为基础的分类系统（IOTF和德国参考）和样本为基础的WC cutoffs.Results：BMI以及WC表现良好，在检测多余的脂肪量，所示的ROC曲线下面积（AUC）接近1.0，略大于AUC的BMI比WC在两种性别。所有参考系统对两种性别的特异性均较高（95 - 98%）。然而，他们的敏感性很低（男孩为53-67%;女孩为51-67%）。PPV较高的德国参考和样本为基础的WC截止比IOTF参考，女孩比boy.Conclusions：设置中的参考系统应使用的参考系统的选择是很重要的。研究结果支持在流行病学研究中使用基于BMI的参考品进行监测。WC的基于样本的临界值应在国家层面上进行完善，以供临床使用。欧洲临床营养学杂志（2011）65，151-159; doi：10.1038/ejcn.2010.245; 2010年11月3日在线发表
Background/Objectives: To evaluate the screening performance of body mass index (BMI) and waist circumference (WC) for excess adiposity. In addition, the diagnostic accuracy of cutoffs from different international and national reference systems based on BMI and WC was investigated.Subjects/Methods: Data from 2132 Jena children aged 7-14 years conducted in 2005/2006 were analyzed. Receiver operating characteristic (ROC) curves were constructed to assess BMI and WC, as screening measures for excess adiposity (derived from skinfolds). Sensitivity, specificity and positive predictive values (PPVs) were calculated for two BMI-based classification systems (IOTF and German reference) and sample-based WC cutoffs.Results: The BMI as well as the WC performed well in detecting excess fat mass, indicated by areas under the ROC curve (AUC) close to 1.0, with slightly greater AUCs for BMI than for WC in both sexes. The specificity of all reference systems was high for both sexes (95 to 98%). However, their sensitivities were low (53-67% in boys; 51-67% in girls). PPV were higher for the German reference and the sample-based WC cutoffs than for the IOTF reference, and higher in girls than in boys.Conclusions: The setting in which the reference system should be used is important for the selection of the reference system. The results support the use of the BMI-based references for monitoring in epidemiological studies. The sample-based cutoffs for WC should be refined for clinical use on national level. European Journal of Clinical Nutrition (2011) 65, 151-159; doi:10.1038/ejcn.2010.245; published online 3 November 2010