Trans-oceanic genomic divergence of Atlantic cod ecotypes is associated with large inversions.
Trans-oceanic genomic divergence of Atlantic cod ecotypes is associated with large inversions.
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DOI：
10.1038/hdy.2017.54
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发表时间：
2017-12
期刊：
影响因子：
3.8
通讯作者：
Jakobsen KS
中科院分区：
文献类型：
--
作者：
Berg PR;Star B;Pampoulie C;Bradbury IR;Bentzen P;Hutchings JA;Jentoft S;Jakobsen KS
染色体重排（例如倒位）在维持复杂性状背后的多态性方面发挥着至关重要的作用，并有助于物种形成过程。在大西洋鳕鱼（Gadus morhua）中，已发现数个巨碱基倒位主导了东北大西洋洄游和非洄游生态型之间的基因组分化。在这里，我们发现相同的基因组区域表现出较高的分化，并导致西北大西洋的生态型分化。大西洋两岸发生的这些逆转揭示了共同的进化起源，早于大西洋鳕鱼跨大西洋分离的 100 万年以上。这些倒位的长期持续存在表明它们是通过选择维持的，可能是通过复杂性状背后的基因的共同进化来促进的。我们的数据表明，迁徙行为源自更固定的祖先生态类型。总体而言，我们确定了几个大型基因组区域（每个区域包含数百个基因），这些区域可能与大西洋两岸大西洋鳕鱼基因组分歧的维持有关。
Chromosomal rearrangements such as inversions can play a crucial role in maintaining polymorphism underlying complex traits and contribute to the process of speciation. In Atlantic cod (Gadus morhua), inversions of several megabases have been identified that dominate genomic differentiation between migratory and nonmigratory ecotypes in the Northeast Atlantic. Here, we show that the same genomic regions display elevated divergence and contribute to ecotype divergence in the Northwest Atlantic as well. The occurrence of these inversions on both sides of the Atlantic Ocean reveals a common evolutionary origin, predating the >100 000-year-old trans-Atlantic separation of Atlantic cod. The long-term persistence of these inversions indicates that they are maintained by selection, possibly facilitated by coevolution of genes underlying complex traits. Our data suggest that migratory behaviour is derived from more stationary, ancestral ecotypes. Overall, we identify several large genomic regions—each containing hundreds of genes—likely involved in the maintenance of genomic divergence in Atlantic cod on both sides of the Atlantic Ocean.
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影响因子：
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作者：
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