Salivary gland tumours
Salivary gland tumours
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DOI：
10.1034/j.1601-0825.2002.02870.x
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发表时间：
2002-09-01
期刊：
影响因子：
3.8
通讯作者：
Barrett, AW
中科院分区：
文献类型：
--
作者：
Speight, PM;Barrett, AW
唾液腺肿瘤是一种相对罕见且形态多样的病变。虽然大多数临床医生和病理学家会遇到更常见的良性肿瘤，很少有经验的全方位的唾液腺癌，这是最好的管理在专科中心。这篇综述考虑了目前在这些肿瘤的诊断和治疗中存在的一些困难和争议。这些病变的分类是复杂的，包括近40个不同的实体，但精确的分类和术语是必不可少的准确诊断和肿瘤预后组的分配。对于许多唾液腺肿瘤的诊断是简单的，但肿瘤类型之间和肿瘤类型内的广泛的形态多样性意味着诊断可能不可能在小切口活检和仔细考虑的临床和病理特征是必不可少的。虽然肿瘤分级是重要和有帮助的，但它不是一个独立的预后指标，必须在分期的背景下考虑。大的恶性肿瘤往往预后不良，无论级别如何，即使是高级别的肿瘤，当它们很小时也可能表现良好。一个有用的指导唾液腺癌的管理是“4厘米规则”。
Salivary gland tumours are a relatively rare and morphologically diverse group of lesions. Although most clinicians and pathologists will have encountered the more common benign neoplasms, few have experience of the full range of salivary cancers, which are best managed in specialist centres. This review considers some current areas of difficulty and controversy in the diagnosis and management of these neoplasms. The classification of these lesions is complex, encompassing nearly 40 different entities, but precise classification and terminology is essential for an accurate diagnosis and for the allocation of tumours to prognostic groups. For many salivary tumours diagnosis is straightforward but the wide range of morphological diversity between and within tumour types means that a diagnosis may not be possible on small incisional biopsies and careful consideration of the clinical and pathological features together is essential. Although tumour grading is important and helpful, it is not an independent prognostic indicator and must be considered in the context of stage. Large malignancies tend to have a poor prognosis regardless of grade and even high-grade neoplasms may do well when they are small. A helpful guide to management of salivary cancers is the '4 cm rule'.