Colorimetry for wall appearance study of cerebral aneurysms
Colorimetry for wall appearance study of cerebral aneurysms
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比色法用于脑动脉瘤壁外观研究
DOI：
10.1016/j.hest.2021.10.002
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发表时间：
2022
影响因子：
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通讯作者：
Takenori Sato，Yoichi Miura，Ryuta Yasuda，Naoki Toma，Hidenori Suzuki
中科院分区：
文献类型：
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作者：
Kawamoto Eiji;Ito-Masui Asami;Esumi Ryo;Imai Hiroshi;Shimaoka Motomu;Takenori Sato，Yoichi Miura，Ryuta Yasuda，Naoki Toma，Hidenori Suzuki
背景：神经外科医生可以在显微外科手术过程中评估脑动脉瘤的薄红壁，但对颜色的判断是主观的，可能存在偏差。本研究旨在定量评估动脉瘤壁特征。方法：在15个未破裂脑动脉瘤中，使用Commission International del’Eclairage L* a* b*测量脑动脉瘤、载瘤动脉和分支的表面颜色。将L*（感知亮度）、a*（红绿颜色特征）和b*（蓝黄颜色特征）的值与两位独立神经外科医生的颜色辨别进行比较，将其分为“红色”、“黄色”、“白色”和“未判断”。结果：与黄或白壁点相比，两位神经外科医生一致判断的红墙点显示出较低的L*和较高的a*值，而b*值则显着降低。值无显着差异。基于这些结果，开发了一种新的指标，动脉瘤红色指标 (ARI)，作为 a* 与 L* 值的比率。 ARI对区分红壁具有较高的敏感性和特异性（分别为0.984和0.986）。结论：ARI可用于评估脑动脉瘤的薄红壁。使用比色法的新方法可能有助于未来与动脉瘤壁特征相关的血流动力学分析。
Background: Neurosurgeons can assess thin red walls in a cerebral aneurysm during a microsurgical procedure, but the judgment of the color is subjective and could have a bias. This study aimed to quantitatively evaluate the aneurysm wall characteristics.Methods: In 15 unruptured cerebral aneurysms, the surface color of cerebral aneurysms, parent arteries and branches were measured using Commission International del’Eclairage L* a* b*. The values of L*(perceptual lightness), a*(red-green color characteristics) and b*(blue-yellow color characteristics) were compared with color discrimination by two independent neurosurgeons, which was classified into ‘‘red”,‘‘yellow”,‘‘white” and ‘‘unjudged”.Results: Significantly lower L* and higher a* values were shown in red wall points consistently judged by both neurosurgeons compared with yellow or white wall points, while b* values had no significant differences. Based on these results, a novel index, aneurysm red indicator (ARI) was developed as a ratio of a* to L* values. The ARI had a high sensitivity and specificity to discriminate red walls (0.984 and 0.986, respectively).Conclusions: ARI could be useful for evaluating thin red walls of cerebral aneurysms. The novel approach using colorimetry may contribute to future hemodynamics analyses related to the aneurysm wall characteristics.