Cell healing: Calcium, repair and regeneration.
Cell healing: Calcium, repair and regeneration.
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DOI：
10.1016/j.semcdb.2015.09.026
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发表时间：
2015-09
影响因子：
7.3
通讯作者：
Bement WM
中科院分区：
文献类型：
--
作者：
Moe AM;Golding AE;Bement WM
细胞修复由于其保护性、对健康的重要性以及作为细胞信号传导和细胞极化模型的实用性而引起越来越多的关注。然而，关于细胞修复的一些最基本的问题尚未得到回答。在这里，我们考虑三个这样的问题：1）如何伤口孔停止？2)受伤后如何实现细胞再生？3)钙涌入如何与伤口停止和细胞再生联系在一起？
Cell repair is attracting increasing attention due to its conservation, its importance to health, and its utility as a model for cell signaling and cell polarization. However, some of the most fundamental questions concerning cell repair have yet to be answered. Here we consider three such questions: 1) How are wound holes stopped? 2) How is cell regeneration achieved after wounding? 3) How is calcium inrush linked to wound stoppage and cell regeneration?