Evidence for the use of the Mediterranean diet in patients with CHD
Evidence for the use of the Mediterranean diet in patients with CHD
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DOI：
10.1017/s0029665109991856
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发表时间：
2010-02-01
影响因子：
7
通讯作者：
Woodside, Jayne V.
中科院分区：
文献类型：
--
作者：
McKeown, Pascal P.;Logan, Karen;Woodside, Jayne V.
饮食与冠心病的发生发展密切相关。南欧国家的CHD发病率低于北欧国家，有人认为这种差异可能是饮食的结果。传统的地中海饮食强调水果、蔬菜、面包、其他形式的谷类食品、土豆、豆类、坚果和种子的高摄入量。它包括橄榄油作为主要的脂肪来源，乳制品、鱼和家禽的消费量从低到中等。许多观察性研究表明，地中海饮食与降低冠心病风险有关，这一结果已被荟萃分析证实，而单一的随机对照试验--里昂饮食心脏研究--显示，在二级预防环境中，遵循地中海饮食的受试者患冠心病的风险降低。然而，鉴于自里昂饮食心脏研究进行以来，在冠心病患者中看到的药物治疗的变化，地中海饮食的好处是否可以转移到其他非地中海人群，以及地中海饮食的效果是否仍然可行，尚不确定。还需要进一步的随机对照试验，如果降低风险的效果得到证实，那么需要考虑在全球范围内有效传递这一公共卫生信息的最佳方法。
Diet is associated with the development of CHD. The incidence of CHD is lower in southern European Countries than in northern European countries and it has been proposed that this difference may be a result of diet. The traditional Mediterranean diet emphasises a high intake of fruits, vegetables, bread, other forms of cereals, potatoes, beans, nuts and seeds. It includes olive oil as a major fat source and dairy products, fish and poultry are consumed in low to moderate amounts. Many observational Studies have shown that the Mediterranean diet is associated with reduced risk of CHD, and this result has been confirmed by meta-analysis, while a single randomised controlled trial, the Lyon Diet Heart study, has shown a reduction ill CHD risk in subjects following the Mediterranean diet in the secondary prevention setting However, it is uncertain whether the benefits of the Mediterranean diet are transferable to other non-Mediterranean populations and whether the effects of the Mediterranean diet will still be feasible in light of the changes in pharmacological therapy seen in patients with CHD since the Lyon Diet Heart study was conducted. Further randomised controlled trials are required and if the risk-reducing effect is confirmed then the best methods to effectively deliver this public health message worldwide need to be considered.