Asthma-related deaths.
Asthma-related deaths.
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DOI：
10.1186/s40248-016-0073-0
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发表时间：
2016
影响因子：
2.3
通讯作者：
D'Amato M
中科院分区：
文献类型：
--
作者：
D'Amato G;Vitale C;Molino A;Stanziola A;Sanduzzi A;Vatrella A;Mormile M;Lanza M;Calabrese G;Antonicelli L;D'Amato M
尽管在哮喘治疗方面取得了重大进展，并制定了一些哮喘指南，但目前仍有人死于哮喘。据世卫组织估计，每年约有25万人过早死于哮喘。哮喘死亡率的趋势在不同国家、年龄和种族群体之间差异很大。几个危险因素与哮喘死亡率相关，包括需要插管和机械通气的近致命哮喘病史，过去一年因哮喘住院或急诊，目前使用或最近停止使用口服皮质类固醇（事件严重程度的标志物），目前未使用吸入性皮质类固醇，有精神疾病或心理社会问题史，对哮喘药物的依从性差和/或对书面哮喘行动计划的依从性差（或缺乏），哮喘患者的食物过敏。在大多数哮喘死亡中已经确定了可接受的因素。当哮喘控制不佳时，对患者认识风险和采取适当行动的教育不足，哮喘诊断的准确性和时间不足，严重程度和治疗分类不充分，似乎在大多数哮喘死亡中发挥了作用。通过使用指导性自我管理护理系统来改善管理可能是降低全球哮喘死亡率的关键目标
Despite major advances in the treatment of asthma and the development of several asthma guidelines, people still die of asthma currently. According to WHO estimates, approximately 250,000 people die prematurely each year from asthma. Trends of asthma mortality rates vary very widely across countries, age and ethnic groups. Several risk factors have been associated with asthma mortality, including a history of near-fatal asthma requiring intubation and mechanical ventilation, hospitalization or emergency care visit for asthma in the past year, currently using or having recently stopped using oral corticosteroids (a marker of event severity), not currently using inhaled corticosteroids, a history of psychiatric disease or psychosocial problems, poor adherence with asthma medications and/or poor adherence with (or lack of) a written asthma action plan, food allergy in a patient with asthma. Preventable factors have been identified in the majority of asthma deaths. Inadequate education of patients on recognising risk and the appropriate action needed when asthma control is poor, deficiencies in the accuracy and timing of asthma diagnosis, inadequate classification of severity and treatment, seem to play a part in the majority of asthma deaths. Improvements in management, epitomized by the use of guided self-management systems of care may be the key goals in reducing asthma mortality worldwide